In 1758 he published the Tableau économique (Economic Table), which provided the foundations of the ideas of the Physiocrats. This was perhaps the first work to attempt to describe the workings of the economy in an analytical way, and as such can be viewed as one of the first important contributions to economic thought.
The publications in which Quesnay expounded his system were the following: two articles, on "Fermiers" and on "Grains", in the Encyclopédie of Diderot and D'Alembert (1756, 1757); a discourse on the law of nature in the Physiocratie of Dupont de Nemours (1768); Maximes générales de gouvernement economique d'un royaume agricole (1758), and the simultaneously published Tableau économique avec son explication, ou extrait des économies royales de Sully (with the celebrated motto, Pauvres paysans, pauvre royaume; pauvre royaume, pauvre roi); Dialogue sur le commerce et les travaux des artisans; and other minor pieces.
The Tableau économique, though on account of its dryness and abstract form it met with little general favor, may be considered the principal manifesto of the school. It was regarded by the followers of Quesnay as entitled to a place amongst the foremost products of human wisdom, and is named by the elder Mirabeau, in a passage quoted by Adam Smith, as one of the three great inventions which have contributed most to the stability of political societies, the other two being those of writing and of money. Its object was to exhibit by means of certain formulas the way in which the products of agriculture, which is the only source of wealth, would in a state of perfect liberty be distributed among the several classes of the community (namely, the productive classes of the proprietors and cultivators of land, and the unproductive class composed of manufacturers and merchants), and to represent by other formulas the modes of distribution which take place under systems of Governmental restraint and regulation, with the evil results arising to the whole society from different degrees of such violations of the natural order. It follows from Quesnay's theoretic views that the one thing deserving the solicitude of the practical economist and the statesman is the increase of the net product; and he infers also what Smith afterwards affirmed, on not quite the same ground, that the interest of the landowner is strictly and indissolubly connected with the general interest of the society. A small edition de luxe of this work, with other pieces, was printed in 1758 in the Palace of Versailles under the king's immediate supervision, some of the sheets, it is said, having been pulled by the royal hand. Already in 1767 the book had disappeared from circulation, and no copy of it is now procurable; but, the substance of it has been preserved in the Ami des hommes of Mirabeau, and the Physiocratie of Dupont de Nemours.
His economic writings are collected in the 2nd vol. of the Principaux économistes, published by Guillaumin, Paris, with preface and notes by Eugène Daire; also his OEuvres économiques et philosophiques were collected with an introduction and note by August Oncken (Frankfort, 1888); a facsimile reprint of the Tableau économique, from the original MS., was published by the British Economic Association (London, 1895). His other writings were the article "Évidence" in the Encyclopédie, and Recherches sur l'évidence des vérites geometriques, with a Projet de nouveaux éléments de géometrie, 1773. Quesnay's Eloge was pronounced in the Academy of Sciences by Grandjean de Fouchy (see the Recueil of that Academy, 1774, p. 134). See also F.J. Marmontel, Mémoires; Mémoires de Mme. du Hausset; H. Higgs, The Physiocrats (London, 1897).